Contents
What is Resveratrol?
- A natural polyphenol found in the skin of grapes, red wine, berries, and peanuts.
- Known for its powerful antioxidant, anti-aging, and anti-inflammatory properties.
- Investigated for its role in cellular protection, metabolic health, and longevity support.
Main Benefits
| Health Area | Effects |
|---|---|
| Longevity and Aging | Activates sirtuins (SIRT1), supporting healthy aging processes |
| Heart Health | Improves endothelial function, reduces blood pressure |
| Antioxidant Defense | Protects cells from oxidative stress |
| Brain Health | May support memory, cognitive function, and protect neurons |
| Metabolic Health | Enhances insulin sensitivity and mitochondrial function |
Typical Dosage
- 100 to 500 mg/day for general antioxidant and health support.
- 500 to 1,000 mg/day sometimes used in clinical studies targeting inflammation or aging-related conditions.
- Often combined with piperine (from black pepper) to improve absorption.
Best Time to Take
- Take with meals containing fat to enhance absorption.
- Morning or midday is typically preferred to align with natural sirtuin activation rhythms.
Possible Side Effects
- Generally well tolerated at moderate doses.
- Higher doses may cause mild digestive upset, diarrhea, or joint aches in some individuals.
- May interact with blood thinners (e.g., warfarin) and other medications; consult a healthcare provider if concerned.
Natural Food Sources
- Red grapes and red wine
- Blueberries
- Cranberries
- Peanuts
- Dark chocolate
Note: Dietary intake levels are low compared to amounts studied for therapeutic purposes, so supplementation is often used for higher dosing.
Buying Tips
- Look for trans-resveratrol, the most bioactive form.
- Choose supplements with micronized resveratrol or liposomal delivery for better absorption.
- Some formulations combine resveratrol with quercetin to enhance stability and effectiveness.
